Thursday, July 18, 2019

Amino Acids in Human Nutrition and Health

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Research interest in the biochemistry of amino acids continues apace, generating significant dividends for nutritional support and the elucidation of mechanisms underlying a variety of disorders in humans. The remarkable scale of recent developments has provided the impetus for publication of this first edition of Amino Acids in Human Nutrition and Health. It was deemed appropriate to formally acknowledge these advances within a comprehensive volume. The recruitment of authors with exceptional merit constituted an integral part of my strategy.

There appears to be a demand for a book which integrates recent advances relating to amino acids within the two disciplines of nutrition and health. Various symposia have been convened on certain aspects covered in this book, but the published proceedings are distributed in different issues of journals, thereby compromising convenience for consultation by students and research staff. It is an unfortunate reflection of our time that university libraries cannot afford to stock some of the primary journals that have, in the recent past, been judged to be essential reading for advanced students. The publication of Amino Acids in Human Nutrition and Health might be viewed as an attempt to rectify this deficiency. Furthermore, the symposia have focused on restricted themes, whereas this volume is designed to address a comprehensive range of issues. The reviews in published proceedings of symposia have also been restricted to a few pages per article, but there is a need for in-depth coverage to more appropriately reflect current developments.

1. Glutamate Dehydrogenase
2. Aminotransferases
3. Arginase
4. Bypassing the Endothelial L-Arginine-Nitric Oxide Pathway: Effects of Dietary Nitrite and Nitrate on Cardiovascular Function
5. Histidine Decarboxylase
6. Glutamate Decarboxylase
7. Glutaminase
8. D-Serine and Serine Racemase in the Retina
9. Tryptophan Hydroxylase
10. Methionine Metabolism
11. Amino Acid Transport Across Each Side of the Blood-Brain Barrier
12. Inter-organ Fluxes of Amino Acids
13. Cellular Adaptation to Amino Acid Availability: Mechanisms Involved in the Regulation of Gene Expression
14. Endogenous Amino Acids at the Terminal Ileum of the Adult Human
15. Metabolic Availability of Amino Acids in Food Proteins: New Methodology
16. Amino Acid Requirements: Quantitative Estimates
17. Amino Acid Supplements and Muscular Performance
18. Amino Acids in Clinical and Nutritional Support: Glutamine in Duchenne Muscular Dystrophy
19. Adverse Effects
20. The Umami Taste of Glutamate
21. Homocysteine Status: Factors Affecting and Health Risks
22. Modified Amino Acid-Based Molecules: Accumulation and Health Implications
23. Phenylketonuria: Newborn Identification Through to Adulthood
24. Principles of Rapid Tryptophan Depletion and its Use in Research on Neuropsychiatric Disorders
25. Excitatory Amino Acids in Neurological and Neurodegenerative Disorders
26. Efficacy of L-DOPA Therapy in Parkinson's Disease
27. Amino Acid Profiles for Diagnostic Applications
28. Emergence of a New Momentum

Author Details
"J.P.F. D'MeIIo"

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